4,4'-Diamino-2,2'-stilbenedisulfonic acid Property

Melting point:

300 °C

Density 

1.4732 (rough estimate)

vapor pressure 

1.3hPa at 25℃

refractive index 

1.6510 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

Aqueous Base (Slightly)

pka

-1.58±0.50(Predicted)

form 

Crystalline Powder

color 

Cream to yellow-brown

Water Solubility 

<0.1 g/100 mL at 23 ºC

Merck 

14,595

BRN 

629516

Stability:

Stable. Combustible. Incompatible with iron, strong oxidizing agents.

LogP

-1.7--1.42 at 25℃

CAS DataBase Reference

81-11-8(CAS DataBase Reference)

EPA Substance Registry System

Amsonic acid (81-11-8)

Safety

Hazard Codes 

C,Xn

Risk Statements 

34-22-36/37/38-20/21/22

Safety Statements 

24/25-45-36/37/39-26-22

RIDADR 

UN 2583

RTECS 

WJ6603000

TSCA 

Yes

HS Code 

29215900

Hazardous Substances Data

81-11-8(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

4,4'-Diamino-2,2'-stilbenedisulfonic acid Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Powder

Uses

4,4’-Diaminostilbene-2,2’-disulfonic Acid, 95+% (cas# 81-11-8) is a compound useful in organic synthesis.

Uses

In manufacture of dyes, bleaching agents.

General Description

Odorless yellowish microscopic needles or cream-colored powder. pH approximately 4.3 at 30 g/L water (suspension).

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4,4'-Diamino-2,2'-stilbenedisulfonic acid is incompatible with iron. 4,4'-Diamino-2,2'-stilbenedisulfonic acid forms sparingly water-soluble, crystalline salts with many bisquaternary ammonium bases.

Fire Hazard

Flash point data for 4,4'-Diamino-2,2'-stilbenedisulfonic acid are not available; however, 4,4'-Diamino-2,2'-stilbenedisulfonic acid is probably combustible.

Synthesis

A typical procedure for preparation of 4,4'-Diamino-2,2'-stilbenedisulfonic acid: A solution of potassium hydroxide (3 g, 52 mmol) in a low amount of water was slowly added with stirring to a mixture of p-nitrotoluene ortho sulfonic acid (2.2 g, 10 mmol), diethylene glycol (20 mL) and 2.5 mL of hydrazine hydrate 85%. The resulting mixture was refluxed for 30 minutes, then the condenser was removed, the aqueous liquor evaporated, and refluxing continued for 2.5 hours. The reaction mixture was cooled and diluted with water when the reaction was completed. Then, the cooled and diluted reaction mixture was acidified with warm, concentrated hydrochloric acid, and the pure product was filtered.

Environmental Fate

For the environment, various NOEC and LC50 values were gained from test results; LC50 = > 1000 mg/l (acute fish); EC50 = 210 mg/l (acute daphnia); EC50 = 76 mg/l (acute algae); NOEC = 32 mg/l (algae); NOEC = 37 mg/l (longterm daphnia reproduction). The lowest toxicity result (72h-NOEC, biomass, for Selenastrum capricornutum, 32 mg/l) was used to derive a PNEC. An assessment factor of 100 was used according to the OECD Provisional Guidance for Initial Assessment of Aquatic Effects. Thus, PNEC of 4,4'-Diamino-2,2'-stilbenedisulfonic acid is 0.32 mg/l in the present report. The PEC is lower than the PNEC. The environmental risk is presumed to be low.